Fertility: The Male Factor

Conception and Male Fertility

Historical update of semen quality

• 1940 the lower reference value for a ‘normal’ sperm count was 113 x 10⁶/mL¹
• 1990 the lower reference value for a ‘normal’ sperm count was 60 x 10⁶/mL¹
• 2010 the World Health Organization (WHO) reduced the lower reference value for sperm concentration ensuring more men fell into ‘normal values.’ The lower reference value for sperm concentration is 15 x 10⁶/mL sperm per mL (95% CI 12-16). This replaces the current limit of 20 x 10⁶/mL²

Concentration is related to time to pregnancy³

• Data showed 15% of couples could not conceive a child after one year of regular unprotected intercourseǂ
• Male factor is solely responsible in about 20% of couples^ǂ

Male factor contributes in another 30% of couples, therefore male factor is responsible in up to 50% of couplesǂ

Fertility – Nutrients and Sperm Quality

A prenatal male fertility supplement Proxeed plus is a complete formulation designed to support multiple sperm qualities^ǂ

Supporting normal sperm development

Proxeed plus is a potent prenatal male fertility supplement that targets specific metabolic functions involved in sperm metabolism.^ǂ

• Oxidative Stress contributes to changes in spermatogenesis that affect male fertility^ǂ4
• Antioxidants are the most important support for free radical balance and male fertility^ǂ
• Carnitines have the most clinical support compared to all the other nutrients in the field of male fertility^ǂ
  • Some patients have lower levels of L-Carnitine (LC) and acetyl-L-carnitine (ALC) in seminal plasma
  • In men, a balanced L-Carnitine/Acetyl-L-carnitine ratio can help:
    • Maintain seminal plasma levels^ǂ
    • Maintain sperm health^ǂ
    • Maintain sperm quality, an essential factor in a couple’s fertility^ǂ

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